Wrexham sit sixth in the Championship after one loss in six
Portsmouth have won their last two away games by 3-1 scorelines
Recommended bet: Wrexham to win
Wrexham delivered an excellent performance last time out against Ipswich Town, sealing a 5-3 victory over the East Anglian side to maintain their Championship promotion ambitions.
The Red Dragons currently have 51 points and sit two points clear of Birmingham City in seventh place.
At the other end of the table, Portsmouth are fighting to maintain their second tier status for next season.
While they remain six points above the drop zone, a loss in north Wales, combined with other results going against them, means Pompey could be back in more trouble.
The latest Wrexham vs Portsmouth odds are available on LiveScore Bet
Team news
Phil Parkinson will have to make do without Ben Sheaf for this clash as he was taken off during the win over the Tractor Boys.
Zak Vyner is nearing a return to action, but he is not quite ready or this match, while Liberato Cacace and Matty James will not be available for at least another couple of weeks.
Pompey are in the middle of an injury crisis, with 12 players currently unavailable for this fixture.
Josh Murphy, Keshi Anderson, Florian Bianchini, Franco Umh, Thomas Waddingham and Conor Chaplin are all ruled out.
Meanwhile, Hayden Matthews, Conor Shaughnessy, Mark Kosznovszky, Josh Knight, Andre Dozzell and Aji Alese remain on the sidelines for John Mousinho.
The stats
These two sides played out a drab goalless draw in the reverse fixture at Fratton Park back in November and that was the first meeting between the two teams since 1986.
Overall, Wrexham have won just four games against Pompey dating back to 1976. Their last victory over the south coast side came in 1978.
Wrexham have one of the best attacking records in the second tier, with only Coventry and Ipswich scoring more than their 51 goals this term.
Pompey, on the other hand, have found the back of the net on just 33 occasions, the fifth-worst record in the Championship.
The Red Dragons have won seven games since the start of 2026, suffering just two defeats in the process.
Mousinho's men have won their previous two league matches, winning four of the 10 fixtures they have played in 2026.
The latest Wrexham vs Portsmouth odds are available on LiveScore Bet
Prediction
The result of this clash could have implications at both ends of the table.
A win for Wrexham will allow them to maintain hopes of yet another promotion, something which seemed unlikely at the beginning of the campaign.
For Portsmouth, losing might well drag them into a proper relegation fight, something that they will be hoping to avoid.
Buoyed by the stunning win over Ipswich last time out, the Red Dragons will head into this game brimming with confidence that they can seal another three points.
Given that the away side are plagued with injuries, Parkinson's men should have enough to claim the win.
