The United States' position as the heavy favourites to win the Ryder Cup was vindicated as they claimed a 3-1 lead after the foursomes.
Though the first point at Whistling Straits went to Europe's Sergio Garcia and Jon Rahm, the other three matches were dominated by the hosts in Wisconsin.
Victories for the pairs of Dustin Johnson and Collin Morikawa, Brooks Koepka and Daniel Berger and Patrick Cantlay and Xander Schauffele left Europe with significant work to do in the fourballs as they bid to retain the cup.
The weight of expectation is firmly on the USA; however, after the Americans rose to the challenge in the opening session, the onus switches to Europe's captain Padraig Harrington, who was eyeing an afternoon improvement to prevent his team slipping to a potentially decisive deficit.
Garcia and Rahm might have feared the worst when the former drove into the bunker off the opening tee.
However, Garcia was superb with the driver thereafter and Rahm excelled with the flat stick as they claimed their match against Justin Spieth and Justin Thomas 3 and 1.
Yet the form that all-Spanish duo produced could not be replicated by their European team-mates.
Morikawa and Johnson soon levelled matters following Garcia and Rahm's triumph, their victory secured when Morikawa converted a short putt from 22 inches on the 16th to defeat Viktor Hovland, who missed a long putt for birdie to keep the match alive, and Paul Casey.
Patrick Cantlay and Xander Schauffele were in command throughout against two Ryder Cup mainstays in Rory McIlroy and Ian Poulter.
The American pair won the first five holes and, despite a brief comeback from McIlroy and Poutler, prevailed 5 and 3.
And, while Rahm thrived on the green, Lee Westwood and Matt Fitzpatrick could not buy a putt in their loss to Daniel Berger and Brooks Koepka, whose 2 and 1 success put the USA 11.5 points from regaining the cup.
Friday's foursomes results
Jon Rahm and Sergio Garcia (EUR) beat Justin Thomas and Jordan Spieth (USA) 3 and 1
Dustin Johnson and Collin Morikawa (USA) beat Paul Casey and Viktor Hovland (EUR) 3 and 2
Brooks Koepka and Daniel Berger (USA) beat Lee Westwood and Matt Fitzpatrick (EUR) 2 and 1
Patrick Cantlay and Xander Schauffele (USA) beat Rory McIlroy and Ian Poulter (EUR) 5 and 3