Wales are hoping to make the most of home advantage in Path A as they host Bosnia & Herzegovina in Cardiff
Italy, who failed to qualify for the 2018 and 2022 World Cups, take on Northern Ireland in Bergamo
The Republic of Ireland travel to the Czech Republic in Path D, with the winners facing Denmark or North Macedonia in the final
The final four European qualifiers for the 2026 World Cup will be decided through the play-offs, and Wales, Northern Ireland and the Republic of Ireland are among the 16 teams involved.
We have predictions for the eight semi-finals, which take place on Thursday, and the winners of those ties go through to Tuesday's World Cup play-off finals.
Turkey vs Romania (Thursday, 5pm)
Turkey's talented attackers shone in qualifying Group E as their results included a 6-1 rout of Bulgaria in Sofia and a 2-2 draw with European champions Spain in Seville.
They should be backed to ease past semi-final opponents Romania, who finished third behind Austria and Bosnia & Herzegovina in Group H.
Score prediction: Turkey 3 Romania 1
Czech Republic vs Republic of Ireland (Thursday, 7.45pm)
The Republic of Ireland beat Armenia 1-0, Portugal 2-0 and Hungary 3-2 in their last three Group F qualifiers and they could upset the Czech Republic in the Path D semi-finals.
Ireland are full of confidence and the Czechs look beatable, having lost 5-1 to Croatia and 2-1 to the Faroe Islands in Group L.
Score prediction: Czech Republic 1 Republic of Ireland 2
Denmark vs North Macedonia (Thursday, 7.45pm)
Denmark's dramatic 4-2 defeat to Scotland denied them automatic qualification for the World Cup but they are unlikely to slip up in a home semi-final against North Macedonia.
The visitors were hammered 7-1 by Wales in their final qualifying game and could be outclassed by the Danes in Copenhagen.
Score prediction: Denmark 2 North Macedonia 0
Italy vs Northern Ireland (Thursday, 7.45pm)
Euro 2020 winners Italy are desperate to qualify for this summer's World Cup, having failed to reach the 2018 or 2022 tournaments, and they should sneak past Northern Ireland in Bergamo.
Michael O'Neill's men have claimed most of their best results at Windsor Park and they are missing key defenders Conor Bradley and Dan Ballard.
Score prediction: Italy 2 Northern Ireland 1
Poland vs Albania (Thursday, 7.45pm)
Poland finished as runners-up to the Netherlands in Group G and they can grind out a narrow win over Albania, who conceded only five goals in eight Group K matches – four of them against section winners England.
Score prediction: Poland 1 Albania 0
Slovakia vs Kosovo (Thursday, 7.45pm)
Slovakia beat Germany 2-0, Luxembourg 2-0 and Northern Ireland 1-0 in three home fixtures in Group A and their defensive solidity should help them get past Kosovo in Bratislava.
Score prediction: Slovakia 1 Kosovo 0
Ukraine vs Sweden (Thursday, 7.45pm)
Sweden's Nations League results earned them a second chance in the play-offs after a woeful World Cup qualifying campaign in which they picked up only two points from six games.
Manager Graham Potter has some talented attacking players in his squad but Sweden's defence could let them down against a consistent Ukraine side in Valencia.
Score prediction: Ukraine 2 Sweden 1
Wales vs Bosnia & Herzegovina (Thursday, 7.45pm)
Wales should have star forward Harry Wilson available for their semi-final against Bosnia & Herzegovina and Craig Bellamy's side walloped North Macedonia 7-1 in their last home game.
Another entertaining victory is on the cards against Bosnia, whose only clean sheets in their last nine internationals came against San Marino.
Score prediction: Wales 3 Bosnia & Herzegovina 1
