Title contenders Manchester City host rock-bottom Wolves on Saturday
Aston Villa face a trip to St James' Park to face Newcastle on Sunday
Table-toppers Arsenal host Man Utd in the penultimate fixture of Gameweek 23
The Premier League action comes thick and fast with 10 fixtures taking place from Saturday through to Monday, starting with relegation-threatened West Ham's clash against surprise package Sunderland at the London Stadium.
West Ham vs Sunderland (Saturday, 12.30pm)
West Ham are battling hard to avoid relegation and they may be able to add another point to their tally when hosting Sunderland, who have drawn three of their last five away matches in the league.
Score prediction: West Ham 1-1 Sunderland
Burnley vs Tottenham (Saturday, 3pm)
Burnley are unbeaten in three games in all competitions and they can secure a crucial three points at home to Tottenham, who have won just one of their last eight away fixtures and may be fatigued from Tuesday's Champions League outing.
Score prediction: Burnley 2-1 Tottenham
Fulham vs Brighton (Saturday, 3pm)
Fulham are unbeaten in their last four matches at home, winning three and drawing one, and that strong record at Craven Cottage can see them overhaul Brighton, who are without a win in their last four away assignments in the top-flight.
Score prediction: Fulham 2-1 Brighton
Man City vs Wolves (Saturday, 3pm)
On a two-game losing run, Man City can bounce back in style when they welcome Wolves to the Etihad Stadium, a venue the visitors have lost at in their last five trips.
The Citizens boast the second-best home record in the division, collecting 26 points from 11 matches, and they can stick a few past a Wolves side who are yet to win on the road in the league.
Score prediction: Manchester City 3-0 Wolves
Bournemouth vs Liverpool (Saturday, 5.30pm)
Liverpool have drawn four league matches in a row heading into Saturday's trip to Bournemouth, who have shared the spoils in three of their last six fixtures at the Vitality Stadium. Another draw could be on the cards.
Score prediction: Bournemouth 2-2 Liverpool
Brentford vs Nottm Forest (Sunday, 2pm)
Unbeaten in seven games at the Gtech Community Stadium, Brentford can continue their fantastic home form at the expense of Nottm Forest.
The visitors could be fatigued from Thursday's European defeat and have won just one of their last five away matches.
Score prediction: Brentford 3-1 Nottm Forest
Crystal Palace vs Chelsea (Sunday, 2pm)
Crystal Palace's season is at risk of imploding with the recent sale of Marc Guehi, star striker Jean-Philippe Mateta telling the club he wants to leave this month and manager Oliver Glanser confirming he will leave at the end of the campaign.
The Eagles are without a win in 10 matches as they prepare to host Chelsea, who have shown positive signs under new boss Liam Rosenior and are eyeing a third-successive victory.
Score prediction: Crystal Palace 0-2 Chelsea
Newcastle vs Aston Villa (Sunday, 2pm)
Newcastle are on an eight-game unbeaten run at home in the league and they can secure another massive three points at the expense of Aston Villa, who are without a win in their last two away matches in the top-flight and who have less time to prepare for this contest following Thursday's Europa League win at Fenerbahce.
Score prediction: Newcastle 3-1 Aston Villa
Arsenal vs Man Utd (Sunday, 4.30pm)
Michael Carrick's interim spell in charge of Man Utd started with a derby win over City, but the Red Devils may find life tougher when they head to Arsenal, who have not lost at home this season and who are on a 12-match unbeaten streak.
Score prediction: Arsenal 3-1 Man Utd
Everton vs Leeds (Monday, 8pm)
Leeds have drawn three of their last four away games in the league and another share of the spoils could be on the cards when they head to Everton, who drew 1-1 against Wolves in their last home fixture in the top-flight.
Score prediction: Everton 1-1 Leeds
