Liverpool have won their last three home matches against Brighton
Brighton have not scored in their last two games
Recommended Bet: Liverpool to win 2-0
Liverpool won't have fond memories of the FA Cup fourth round after losing on this weekend last season to Plymouth, who were then relegation strugglers in the Championship.
The Reds boosted their confidence with a 1-0 midweek win at Sunderland in the Premier League, though, and they should be able to avoid any drama when Brighton visit.
The Seagulls are eight places below Liverpool in 14th in the top-flight standings and they have won only two of their 13 away games in the league.
The Reds won 2-0 when Brighton last headed to Anfield in December with a double from Hugo Ekitike and a similar result is likely this time.
Team news
Liverpool will be without Wataru Endo, who was carried off at Sunderland on Wednesday and is expected to be out for several weeks with an ankle injury.
Dominik Szoboszlai can return from suspension and may slot in at right-back to replace him, with Conor Bradley and Jeremie Frimpong still unavailable.
Arne Slot may opt to rest some of his stars, such as Virgil van Dijk, Florian Wirtz and Ekitike, with Joe Gomez, Federico Chiesa and Curtis Jones among those who could come into the starting line-up.
Midfielder Mats Wieffer could be back for Brighton after six weeks out with a toe injury, while Jan Paul van Hecke should also be available after coming through his return appearance at Aston Villa successfully. Jason Steele is likely to start in goal, as he did in the third round.
The latest Liverpool vs Brighton odds are available on LiveScore Bet
The stats
Brighton have lost their last two games to nil.
Liverpool have won four of their last six matches.
Liverpool have scored the first goal in six of their last eight games.
Three of Liverpool's last four wins have been achieved with clean sheets.
Liverpool have scored exactly two goals in five of their last six games against Brighton.
Four of Brighton's last five matches have produced under 2.5 goals.
The latest Liverpool vs Brighton odds are available on LiveScore Bet
Prediction
Brighton overcame a tricky away draw in the third round of the FA Cup when they won 2-1 against Manchester United at Old Trafford but a second long trip to the north-west in the competition may not yield the same result.
The Seagulls have lost their way in recent outings, and are winless in five games since that cup success after defeats to Fulham, Crystal Palace and Aston Villa and 1-1 home draws with Bournemouth and Everton.
They will need to raise their game to cause an upset at Anfield and with goalscoring becoming a problem for Fabian Hurzeler's side, a Liverpool win to nil seems likely.
The Reds won 1-0 at Sunderland in midweek and while manager Slot may take the chance to give some of his big names the day off, he has no real need to make wholesale changes with eight days until their next league game.
Liverpool came out on top 2-0 when the teams met in the league on Merseyside before Christmas and a repeat of that scoreline looks a decent correct-score option as they target a fourth successive home win over Albion.
Back Liverpool to win 2-0 at 6/1 with LiveScore Bet
The latest Liverpool vs Brighton odds are available on LiveScore Bet
