Champions Barcelona are only two points clear of Atletico Madrid at the summit
Real Madrid four points off the top after following up their El Clasico win with another victory
Winless Malaga are joined in the relegation zone by Valencia and Levante
Barcelona bounced back from their El Clasico defeat by routing Alaves 6-1, but the big games keep coming for the leaders as they head to Atletico Madrid for the biggest match of the weekend in Liga.
Sevilla vs Alaves – Friday November 6 (8pm)
Key Stats
Sevilla have won three of their five home games
Alaves are yet to win on the road, picking up only two points from five away days
Team news
Sevilla striker Isaac Romero looks set to miss out alongside Marcao, Miguel Sierra and suspended midfielder Manu Bueno.
Facundo Garces and Mikel Rodriguez are sidelined for the visitors.
Need to know
On paper, Sevilla are on the slide. They have lost three of their last five games and need to arrest that slide.
However, a deeper dive shows that last week's 3-1 loss at Getafe was their first defeat to a side outside of Spain's big three and this looks a golden opportunity to bounce back.
Alaves have avoided defeat in four straight visits to the Ramon Sanchez Pizjuan, but last week's 6-1 hammering at Barcelona is sure to have knocked confidence and their winless away run looks set to go on.
Score prediction: Sevilla 2-0 Alaves @ 7/1 with LiveScore Bet
Malaga vs Racing Santander – Saturday November 7 (1pm)
Key Stats
Malaga are one of only two winless sides in Europe's top five leagues
Racing Santander are unbeaten in six head-to-heads
Team news
Malaga's Angel Recio may return following an illness but Juan Cruz, Julen Lopete, Pablo Martinez and Aaron Ochoa are out and Diego Murillo will be assessed.
Alvaro Mantilla suffered a knee injury in Racing's loss to Real Madrid and has joined Andres Martin in the infirmary. Jorge Salinas is back from suspension.
Need to know
Adrian Nino scored for the fourth LaLiga game in a row in Malaga's loss to Real Betis and the hosts will be hoping their in-form can inspire them to a first victory of the season.
They remain hard to trust, though, and a draw may have to do, with Racing taking four points from last season’s two meetings and losing only two of their last five games.
Score prediction: Malaga 1-1 Racing Santander @ 11/2 with LiveScore Bet
Espanyol vs Deportivo – Saturday November 7 (3.15pm)
Key Stats
Espanyol have been defeated in four of their last six games
Deportivo have lost only three of their 12 games this season
Team news
Espanyol defender Roger Hinojo is suspended and Jofre and Kike Garcia are sidelined, while Marc Casado, Bright Ede and Zakaria Eddahchouri miss out for Deportivo.
Need to know
Espanyol got the new-manager bounce they desired when beating Villarreal 1-0 last time, but Javi Hernandez is not guaranteed to secure a follow-up success.
Deportivo stopped the rot with last weekend’s 2-1 win over Osasuna, a result which was made sweeter by the return of key man Pierre-Emerick Aubameyang.
The Gabonese forward makes La Coruna a much better side and they can show that by earning a point at Espanyol.
Score prediction: Espanyol 1-1 Deportivo @ 21/4 with LiveScore Bet
Osasuna vs Athletic Bilbao – Saturday November 7 (5.30pm)
Key Stats
Osasuna have lost six and won only one of their last eight LaLiga games
Athletic Bilbao have won three matches in a row
Team news
Jorge Herrando and Aimar Oroz miss out for Osasuna, who will also assess Romain Del Castillo.
Unai Egiluz, Gorka Guruzeta and Maroan Sannadi make up Athletic Bilbao’s list of absentees.
Need to know
Fresh from a Basque derby victory over Real Sociedad which made it 12 goals scored in three straight wins, Athletic Bilbao will be full of confidence ahead of this trip to struggling Osasuna.
The hosts lost their manager and best player, Victor Munoz, over the summer and with their second boss of the campaign, Jagoba Arrasate, yet to show anything that results are about to improve, another defeat awaits.
Score prediction: Osasuna 1-3 Athletic Bilbao @ 13/1 with LiveScore Bet
Valencia vs Real Madrid – Saturday November 7 (8pm)
Key Stats
Valencia are yet to win at home, having lost four of their six games
Jose Mourinho has enjoyed 13 wins from his first 15 matches since returning to Real Madrid
Team news
Valencia's Diego Lopez, Sergi Canos and David Otorbi are injured and Jose Copete is a doubt.
Real Madrid are still without injured trio Ferland Mendy, Rodrygo and Raul Asencio, as well as suspended winger Vinicius Junior.
Need to know
Javier Aguirre has brought improved performances to Valencia since replacing Carlos Corberan in the dugout, but few positive results have followed and it is hard to see that trend being bucked against red-hot Real.
Mourinho's men are on a seven-game win streak which has seen them score 25 goals and beat Barcelona in the capital.
Even if Valencia find answers for some of their stars like Kylian Mbappe and Jude Bellingham, someone like Yan Diomande, who has been directly involved in seven goals in as many games, will simply step up instead.
Score prediction: Valencia 0-3 Real Madrid @ 15/2 with LiveScore Bet
Elche vs Real Betis – Sunday November 8 (1pm)
Key Stats
Last week's loss to Valencia was Elche’s first defeat in six games
Real Betis have lost only three of their 15 matches in all competitions
Team news
Thomas Lemar was forced off in Elche's loss to Valencia and is expected to miss out.
Betis are without suspended midfielder Facundo Bernal and injured forward Cucho Hernandez.
Need to know
Elche had shown major signs of improvement during a five-game unbeaten run, but last week's narrow loss to Valencia will have hurt and asking them to bounce back against in-form Betis is a tall order.
A surprise loss at Levante aside, Manuel Pellegrini's Betis have been exceptional and only failed to win their tougher fixtures this season.
They have also beaten Real Madrid along the way and should ease to a ninth win in 13 games.
Score prediction: Elche 0-2 Real Betis @ 19/2 with LiveScore Bet
Real Sociedad vs Rayo Vallecano – Sunday November 8 (3.15pm)
Key Stats
Real Sociedad have lost to only Athletic Bilbao in their last six matches
Rayo Vallecano have also suffered just one defeat in six games
Team news
Alvaro Odriozola and Arsen Zakharyan are certain absentees for Real Sociedad, who must also assess the fitness of Luken Beitia.
Augusto Batalla, Alvaro Garcia, Luiz Felipe and Raul de Tomas make up a lengthy Vallecano injury list.
Need to know
Last week's Basque derby defeat will have knocked Real Sociedad's confidence and there is no guarantee that they bounce back when hosting a very capable Rayo Vallecano.
Rayo are coping impressively well despite the departure of influential manager Inigo Perez and ongoing fan protests and they have the defensive organisation to frustrate their hosts and play their part in a San Sebastian stalemate.
Score prediction: Real Sociedad 1-1 Rayo Vallecano @ 13/2 with LiveScore Bet
Celta Vigo vs Levante – Sunday November 8 (5.30pm)
Key Stats
Five of Celta Vigo's last eight LaLiga games have finished level
Levante have lost only two of their last five matches
Team news
Carl Starfelt, Miguel Roman, Borja Iglesias and Alvaro Nunez make for a packed Celta treatment room, while Enzo Bardeli is Levante's sole absentee.
Need to know
The eight places between this pair at the start of the weekend suggest this should be straightforward for Celta. However, Levante are only two points behind their hosts in a congested LaLiga and may have enough to share the spoils.
Celta are the league's draw specialists – their six stalemates were at least two more than any other side before this round – while Levante have lost to only Atletico Madrid and Real Sociedad in their last five matches.
Score prediction: Celta Vigo 0-0 Levante @ 21/2 with LiveScore Bet
Villarreal vs Getafe – Sunday November 8 (5.30pm)
Key Stats
Villarreal have won only one of their last five games against top-flight opposition
Getafe have lost their last five LaLiga away matches to nil
Team news
Alassane Diatta, Juan Foyth, Ilias Akhomach and Gerard Moreno look set to miss out for the hosts.
Getafe will be without Christantus Uche but will welcome Johan Mojica and Mario Martin back from suspension.
Need to know
Villarreal need to get back on track after a poor run was extended by a 6-0 home hammering at the hands of PSG. Luckily, a home clash against Getafe provides a golden opportunity to do so.
Jose Bordalas' Getafe can be tough to break down when at their best, but their best has very much been reserved for home turf this season and a sixth straight away defeat in the league seems likely.
Score prediction: Villarreal 2-0 Getafe @ 27/5 with LiveScore Bet
Atletico Madrid vs Barcelona – Sunday November 8 (8pm)
Key Stats
Atletico Madrid have won eight and lost only one of their last 10 games
Barcelona have won 13 of their 15 matches this season
Team news
Atletico captain Koke made his return in the week and will be looking to start, but Cristian Romero and Johnny Cardoso remain on the sidelines.
Injuries to Dani Olmo, Roony Bardghji, Xavi Espart, Jules Kounde, Andreas Christensen and Eric Garcia have left the champions six men light for their trip to the capital.
Need to know
After defeats to PSG and bitter rivals Real Madrid, Barcelona have bounced back in style. They hammered Alaves 6-1 before dispatching Aston Villa 3-0 in the Champions League and, led by Lamine Yamal and Raphinha, can put daylight between themselves and Atletico with a win in Madrid.
Diego Simeone's side will not go down without a fight, however.
Atleti have scored at least two goals in six of their last eight wins and have the firepower to ensure LaLiga signs off for the international break with a thriller.
Score prediction: Atletico Madrid 2-3 Barcelona @ 12/1 with LiveScore Bet
