Barcelona are 11 points clear at the top and could be crowned champions this weekend
Second-placed Real Madrid go to Espanyol
Only five points separate Rayo Vallecano in 11th place and Sevilla in relegation zone
Barcelona are on the verge of being crowned LaLiga champions for the second year running and will look to stay firmly on course for the title with a win at Osasuna on Saturday.
At the bottom, the relegation scrap remains tight and two teams in the mix to go down kick off the Spanish action on Friday night when Girona host Real Mallorca.
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Girona vs Real Mallorca (Friday, 8pm)
Girona, in 15th, are four points clear of the relegation zone, so they could do with a win over Mallorca, who are only a point above the bottom three.
This is a huge game at the bottom of the table that looks set to be a closely-fought battle.
Score prediction: Girona 1-1 Real Mallorca
Villarreal vs Levante (Saturday, 1pm)
Third-placed Villarreal can stay in the hunt for Champions League football by getting the better of Levante, who are second-bottom.
The hosts are on a three-game unbeaten run and should be fairly confident of securing all three points at home.
Score prediction: Villarreal 2-0 Levante
Valencia vs Atletico Madrid (Saturday, 3.15pm)
Valencia got a much-needed win over Girona last time to move five points clear of the dropzone but they look set to struggle at home to Champions League semi-finalists Atletico, who are on course for a top-four finish again.
Score prediction Valencia 1-3 Atletico Madrid
Alaves vs Athletic Bilbao (Saturday, 5.30pm)
Alaves are another side in the relegation shake-up as they sit just two places and two points clear of the bottom three.
The home side can secure a huge victory over Athletic Bilbao to further boost their survival hopes, condemning their opponents to a fourth defeat in their last five games.
Score prediction: Alaves 2-1 Athletic Bilbao
Osasuna vs Barcelona (Saturday, 8pm)
It is surely now just a case of when not if Barcelona will be crowned champions and they can edge even closer to the title with a win at Osasuna, who are ninth, two points off the top six.
Score prediction: Osasuna 0-3 Barcelona
Celta Vigo vs Elche (Sunday, 1pm)
Celta Vigo have slipped to seventh after three straight defeats so will be desperate to stop the rot at home to Elche, who are down in 14th and still fearful of relegation.
Elche have posted three successive wins, though, going into this clash and look good enough to earn a point on Sunday.
Score prediction: Celta Vigo 1-1 Elche
Getafe vs Rayo Vallecano (Sunday, 3.15pm)
Getafe are sixth as they chase a European place in LaLiga and they should benefit from taking on a Rayo outfit this weekend who were in UEFA Conference League semi-final action on Thursday.
Getafe have won two of their last three at home and can claim another comfortable victory.
Score prediction: Getafe 3-1 Rayo Vallecano
Real Betis vs Real Oviedo (Sunday, 5.30pm)
Fifth-placed Betis can put another nail in Oviedo's relegation coffin by beating the bottom side at home on Sunday evening.
Betis held Real Madrid to a 1-1 draw in their most recent game and should have too much for the visitors, who have only won six games all season and look destined for the drop.
Score prediction: Real Betis 2-0 Real Oviedo
Espanyol vs Real Madrid (Sunday, 8pm)
Espanyol are yet to pick up a victory in 2026, with their winless run now stretching to 16 games, so it would be a huge shock if they were to get anything against Los Blancos.
Real Madrid must win to mathematically stay in the title race and it should be a comfortable evening for the visitors.
Score prediction Espanyol 0-2 Real Madrid
Sevilla vs Real Sociedad (Monday, 8pm)
Sevilla occupy the final relegation place going into the weekend's games in Spain and time is running out for them to move clear of danger.
A run of five defeats in their last six games is worrying, with Monday's home clash with Real Sociedad, who are eighth, unlikely to bring about a change in fortunes.
Score prediction: Sevilla 0-1 Real Sociedad.
