Leaders Plymouth host fourth-placed Huddersfield in one of the standout fixtures
Robbie Savage will be looking to make it three wins from three as Peterborough manager against Burton
The pressure is mounting on Russell Martin ahead of Leicester's home clash with Doncaster
Mansfield and Oxford got the League One action up and running on Thursday – the U's holding on for a 1-1 draw despite ending the night with just nine men – and there are 11 more matches to look forward to from the third tier on Saturday.
MK Dons vs Luton – Saturday October 17 (12.30pm)
Key stats
MK Dons are the only team yet to pick up a win in League One this season
The Dons have drawn six of their eight league games
Luton have scored 11 of their 16 league goals on their travels
Recommended bet
Team news
MK Dons have defensive injury issues with Kane Wilson and Ryan Barnett sidelined and Curtis Nelson a major doubt. Further forward Rushian Hepburn-Murphy and Callum Patterson look set to miss out again.
Gideon Kodua, Benny Benagr, Jayden Luker, Shayden Morris, Sverre Sandal and Shandon Baptiste all remain unavailable for Luton boss Jack Wilshere.
Need to know
MK Dons are the only team in the EFL yet to pick up a league win this season and they were thrashed 5-1 by Reading on home soil last time out.
Luton have scored in six of their seven away matches across all competitions and their two league wins on the road have seen them put four past both Reading and Wycombe.
Score prediction: MK Dons 1-4 Luton (17/1 with LiveScore Bet)
Peterborough vs Burton – Saturday October 17 (12.30pm)
Key stats
Peterborough have won both their matches under Robbie Savage, scoring seven goals
Burton have failed to score in back-to-back away games in league and cup
The Brewers have only won one of their last eight meetings with Peterborough
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Team news
Rio Adebisi and Samuel Hughes remain long-term absentees for Peterborough, but Declan Frith and Matthew Garbett have both recently returned from layoffs as substitutes and could now be handed starts.
Joe Lewis is out for Burton with a broken toe while defensive partner Kyran Lofthouse is a doubt. Brighton loanee Mark O’Mahony is yet to make an appearance for the club but is closing in on a return to action.
Need to know
Peterborough followed up a 4-1 EFL Trophy victory over Ipswich U21s in Savage's first game in charge with an eye-catching 3-1 success at their new boss' former club Leicester in the league.
Burton have claimed their own win at Leicester this season and beaten leaders Plymouth in their own backyard, but their form has dipped of late and they lost 1-0 at Doncaster last time out.
Score prediction: Peterborough 2-0 Burton (13/2 with LiveScore Bet)
Barnsley vs Cambridge – Saturday October 17 (3pm)
Key stats
Barnsley have taken just a solitary point from the last 12 available in League One
The Tykes are winless in seven matches across all competitions
Cambridge are unbeaten in eight and yet to lose on the road this season
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Team news
Barnsley midfielder Luca Connell will serve the second match of his three-game ban after being sent off against Leicester. Cieran Slicker, Ziyad Larkeche, Makenzie Kirk and Ben Hamed Toure are all out injured.
Callum Stead, Callum Perry and Shane McLoughlin have all been ruled out of this trip to Oakwell for Cambridge.
Need to know
Barnsley are winless in eight and have taken one point from their last four league games, although they did draw with Leicester in their most recent third-tier match at Oakwell.
Cambridge are unbeaten on their travels this season, a run that includes winning at high-flying Bradford, but they have drawn their three other league games on the road.
Score prediction: Barnsley 1-2 Cambridge (13/2 with LiveScore Bet)
Bradford vs Stevenage – Saturday October 17 (3pm)
Key stats
Bradford drew their first match under Michael Duff 0-0 last weekend
The Bantams boast the best defensive record in League One, conceding only five goals
Only Bradford have conceded fewer goals than Stevenage in the division
Recommended bet
Team news
Bradford have no fresh injury concerns and Jake Beesley is expected to be given another chance up front despite scoring just once since his summer arrival from Burton.
Stevenage could name the same side that beat Wigan last weekend. Wanya Marcal scored the only goal in that game and he has netted in all three of his appearances since joining the club last month.
Need to know
Bradford have conceded just five goals in nine league games and eight of their nine matches in the third tier have featured fewer than three goals.
The Bantams played out a 0-0 draw with Leyton Orient last time out, while three of Stevenage's last five league games have finished either goalless or 1-0.
Score prediction: Bradford 0-0 Stevenage (23/4 with LiveScore Bet)
Leicester vs Doncaster – Saturday October 17 (3pm)
Key stats
No team has collected fewer home points in League One than Leicester
The Foxes have lost three of their four league games at the King Power Stadium
Back-to-back league wins have propelled Doncaster up the table
Recommended bet
Team news
Under-fire Leicester boss Russell Martin is expected to ring the changes following last week's home loss to Peterborough with Kamari Doyle, Wes Burns and Ilari Kangasniemi all pushing for starts.
Doncaster will be forced into at least one change after Jordan Thomas picked up a knock in the win over Burton. Experienced forward Will Keane joined on a free transfer during the week and could figure in the matchday squad.
Need to know
The pressure is mounting on Martin with Leicester having won only two of their eight league games. The Foxes have lost their last two league matches at the King Power against Oxford (4-0) and Peterborough (3-1).
Doncaster started the season with a nine-game winless run across league and cup but have now won three on the spin, including league successes over Peterborough and Burton.
Score prediction: Leicester 0-1 Doncaster (23/4 with LiveScore Bet)
Leyton Orient vs Blackpool – Saturday October 17 (3pm)
Key stats
Leyton Orient hold the worst home record in League One
Only two teams have picked up fewer points on the road than Blackpool
Last season's corresponding fixture ended in a 1-1 draw
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Team news
Leyton Orient have no fresh injury concerns to contend with but Oliver Dobin and Demetri Mitchell remain unavailable to head coach Richie Wellens.
Blackpool are boosted by the availability of captain George Honeyman, whose suspension for being sent off at Cambridge last weekend has been overturned. Josh Earl, Niall Ennis, Fraser Horsfall and Michael Ihiekwe remain out for the Seasiders.
Need to know
Both these sides are out of form, Orient winning just one of their last seven across all competitions while Blackpool are without a victory in seven.
Orient also hold the worst home record in the division, while only Mansfield and Wigan have collected fewer points on their travels than Blackpool.
Score prediction: Leyton Orient 1-1 Blackpool (22/5 with LiveScore Bet)
Plymouth vs Huddersfield – Saturday October 17 (3pm)
Key stats
Leaders Plymouth have won five of their last six games in League One
The Pilgrims will be boosted by the return to fitness of top scorer Aribim Pepple
Huddersfield have only lost once in 12 matches across all competitions this season
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Team news
The return of Pepple will be a boost to Plymouth, but Julio Pleguezuelo, Malachi Boateng and Owen Oseni remain sidelined and Joe Edwards is a doubt after coming off against AFC Wimbledon last weekend.
Huddersfield's treatment room remains busy, with Jack Whatmough, David Kasumu, Ryan Ledson and Marcus McGuane all still working their way back to fitness.
Need to know
Plymouth have won five of their last six in League One but two of their three defeats have come on their own patch at Home Park.
Huddersfield surrendered a two-goal lead by conceding two late goals to draw 2-2 with Sheffield Wednesday last time out.
Score prediction: Plymouth 2-2 Huddersfield (7/1 with LiveScore Bet)
Sheffield Wednesday vs AFC Wimbledon – Saturday October 17 (3pm)
Key stats
Sheffield Wednesday have won six and lost none of their last eight games
The Owls have kept three successive home clean sheets
Only Wigan (five) have scored fewer League One goals than AFC Wimbledon (seven)
Recommended bet
Team news
Sil Swinkels, Max Lowe, Tyler Onyango, Jordi Liongola and Louie Barry all remain unavailable for Sheffield Wednesday.
Mathew Stevens is yet to feature for Wimbledon this season and remains out alongside James Tilley. Dujuan Richards and Dan Sweeney are rated as doubts.
Need to know
Sheffield Wednesday have kept three successive home clean sheets, shutting out Wigan and Stockport in the league and Sunderland U21s in the EFL Trophy.
AFC Wimbledon have been efficient this season, as despite only scoring seven goals in nine league games, they have collected a more than respectable 12 points.
Score prediction: Sheffield Wednesday 2-0 AFC Wimbledon (27/5 with LiveScore Bet)
Stockport vs Bromley – Saturday October 17 (3pm)
Key stats
Stockport are one of only two sides to have scored 20 goals in League One
Bromley have conceded 20, the joint-highest amount in the division
The visitors have lost six of their last eight games in all competitions
Recommended bet
Team news
Stockport will be forced into at least one change after midfielder Harry Wood hobbled out of last weekend's come-from-behind win over Barnsley.
Bromley have no fresh injury concerns and JJ McKiernan is expected to lead the line once again as he aims to score for the fourth successive league game.
Need to know
Stockport have scored 20 goals across seven home matches in all competitions and fired home three in the second half of their win over Barnsley.
Bromley have been thumped 7-2 at Sheffield Wednesday already this season but they have managed to score in all four of their League One away trips.
Score prediction: Stockport 3-1 Bromley (13/2 with LiveScore Bet)
Wigan vs Reading – Saturday October 17 (3pm)
Key stats
Wigan are the lowest scorers in League One, netting just five goals
Reading are the division's highest scorers with 22 goals
The Royals have won each of their last four meetings with Wigan
Recommended bet
Team news
Scott Hogan could lead the line for an unchanged Wigan side as he seeks his first league goal for the club after joining on a short-term deal last month.
Reading put five past MK Dons last weekend despite being without League One top scorer Jack Marriott, who remains in the treatment room, as does George Earthy.
Need to know
Wigan have failed to score in their last four League One games and in six of their eight matches in the third tier this season.
Reading scored five for the second time this season in last weekend's 5-1 win at MK Dons, having beaten Mansfield 5-0 on home soil earlier in the campaign.
Score prediction: Wigan 0-2 Reading (7/1 with LiveScore Bet)
Wycombe vs Notts County – Saturday October 17 (3pm)
Key stats
Wycombe’s unbeaten run under Tom Hounsell was ended by Luton last weekend
The Chairboys are one of two teams yet to win at home in League One this season
Notts County have won only one of eight league games
Recommended bet
Team news
After coming on at half time following a difficult first half against Luton, Jack Grimmer and Cauley Woodrow are expected to start for Wycombe on Saturday.
Substitute Rory Finneran scored a late consolation in Notts County's defeat to Oxford last time out and could be rewarded with a starting role.
Need to know
Wycombe won four and lost none of their five games with Hounsell in caretaker charge but were thrashed 4-1 by Luton in his first match as permanent boss. The Chairboys have only kept one clean sheet in 13 games this season.
Notts County have won only once in the league this season but will be buoyed by their midweek 5-1 thrashing of Nottingham Forest U21s in the EFL Trophy.
Score prediction: Wycombe 2-2 Notts County (15/2 with LiveScore Bet)
