
All six Premier League teams can still qualify automatically for the last-16
Barcelona, Man City, Inter Milan, Atletico Madrid and Juventus among teams that start final round outside of top eight
Serie A champions Napoli are in bottom third ahead of their game with Chelsea
The final round of matches in the league phase of the 2025-26 Champions League all take place on Wednesday, with plenty still to play for.
Every one of the 18 matches kick-off at 8pm and it promises to be a thrilling finale.
Arsenal vs Kairat Almaty (Wednesday, 8pm)
The Gunners are the only team that still have a 100% record and are already guaranteed a place in the last-16 of the competition.
Kairat head to London with just one point from seven games and nobody has conceded more goals than the Kazakh club's 19.
Score Prediction: Arsenal 3-0 Kairat Almaty
Barcelona vs FC Copenhagen (Wednesday, 8pm)
The home side are currently outside the top-eight on goal difference and only PSG have beaten Barca on home soil in all competitions this season.
Copenhagen start the week in 26th and can still qualify for the play-offs having collected seven points from their last three matches.
Score Prediction: Barcelona 4-1 FC Copenhagen
Benfica vs Real Madrid (Wednesday, 8pm)
Jose Mourinho’s current club face his former team, with Benfica needing a win and other results to go their way to stand a chance of making the play-offs.
Real, who are third after five wins and two defeats, go into this clash having won each of their last three games in all competitions.
Score Prediction: Benfica 0-2 Real Madrid
Liverpool vs Qarabag (Wednesday, 8pm)
An impressive win at Marseille last week means six-time European champions Liverpool know a victory on Wednesday will seal their place in the top-eight.
Qarabag are 18th and on course for the play-offs, having won three of their opening seven matches.
Score Prediction: Liverpool 3-1 Qarabag
Man City vs Galatasaray (Wednesday, 8pm)
A shock defeat at Bodo/Glimt last week has seen Pep Guardiola’s men slip to 11th, with only one win in their last three European matches.
Galatasaray have picked up just one point from their last three games and gave up 14 shots in their 1-1 home draw with Atletico Madrid last time out.
Score Prediction: Man City 3-1 Galatasaray
Napoli vs Chelsea (Wednesday, 8pm)
The Italians have won just two of their seven Champions League games this term, scoring only seven goals along the way.
Chelsea head to Naples sat in the final automatic qualification spot and having won their last three games in all competitions.
Score Prediction: Napoli 0-2 Chelsea
Paris Saint-Germain vs Newcastle (Wednesday, 8pm)
Nobody has scored more goals than the defending champions going into the final matchday of the league phase, with Luis Enrique’s men finding the net on 20 occasions.
They now host a Newcastle team that are level on points with the French outfit, with Anthony Gordon scoring six times in seven appearances.
Score Prediction: PSG 3-1 Newcastle
Monaco vs Juventus (Wednesday, 8pm)
It’s 21st versus 15th at the Stade Louis II Stadium, with Monaco having failed to win any of their last five Ligue 1 matches.
In contrast, Juventus have lost just one of their last 10 in all competitions, but they have conceded five goals across their previous three European away days.
Score Prediction: Monaco 1-1 Juventus
Bayer Leverkusen vs Villarreal (Wednesday, 8pm)
The German outfit are inside the middle third going into the final round of matches, but their recent lack of goals will be a concern, scoring just once in their last three games.
Despite being fourth in LaLiga, Villarreal have lost five on the spin in Europe and cannot qualify for the latter stages.
Score Prediction: Bayer Leverkusen 1-0 Villarreal
Borussia Dortmund vs Inter Milan (Wednesday, 8pm)
Just one point separates these two teams, with Inter currently 14th, two places ahead of their German hosts.
Nobody in the top-24 has conceded more goals than Dortmund (15), but Niko Kovac’s men have scored six more times than the Serie A giants.
Score Prediction: Borussia Dortmund 2-1 Inter Milan
Eintracht Frankfurt vs Tottenham (Wednesday, 8pm)
Tottenham know a win in Frankfurt will seal their place in the last-16, with Thomas Frank’s men fifth having won three of their last four European ties.
The hosts cannot make it out of the bottom third, with just four points from their seven games, but they are a threat going forward — highlighted by 39 goals in 19 Bundesliga matches.
Score Prediction: Eintracht Frankfurt 1-2 Tottenham
PSV Eindhoven vs Bayern Munich (Wednesday, 8pm)
PSV have slipped to 22nd in the Champions League standings after defeats to Newcastle and Atletico Madrid in their last two matches.
Bayern are guaranteed a place in the knockout stages and Vincent Kompany’s men have scored 92 goals across 26 games in the Bundesliga and in Europe.
Score Prediction: PSV 1-3 Bayern Munich
Atletico Madrid vs Bodo Glimt (Wednesday, 8pm)
After a poor start to their European campaign, Atletico are up to 12th having collected 10 points from their last four games.
A shock win over Man City last time out has kept alive the Norwegians’ hopes of finishing in the middle-third, but they need a win and other results to go for them.
Score Prediction: Atletico Madrid 3-1 Bodo Glimt
Ajax vs Olympiacos (Wednesday, 8pm)
Having lost all of their first five matches, back-to-back wins have kept alive Ajax’s slim hopes of making the play-offs.
The Dutch outfit now face an Olympiacos team that hold the final spot in the middle-third, thanks to wins to nil over Kairat and Bayer Leverkusen.
Score Prediction: Ajax 1-1 Olympiacos
Athletic Bilbao vs Sporting Lisbon (Wednesday, 8pm)
A home draw with PSG and a shock win at Atalanta have moved Athletic Club into 23rd, but they will need another big performance to remain in the play-off places.
Sporting have been arguably the surprise package of the competition, with Rui Borges’ men winning four of their seven matches to date.
Score Prediction: Athletic Bilbao 1-1 Sporting Lisbon
Club Brugge vs Marseille (Wednesday, 8pm)
Two points separate these two teams, with Brugge sat in 27th and Marseille 19th.
Marseille have already won in Belgium this season, with a 3-2 success at Union Saint-Gilloise, but this will be a tougher test.
Score Prediction: Club Brugge 2-2 Marseille
Union Saint-Gilloise vs Atalanta (Wednesday, 8pm)
Both of Union’s league phase wins have come on the road, at PSV and Galatasaray, which will give Atalanta hope of qualifying in the top-eight.
The Serie A outfit are 13th and one of eight teams that are currently sat on 13 points going into the final round.
Score Prediction: Union Saint-Gilloise 0-2 Atalanta
Pafos vs Slavia Prague (Wednesday, 8pm)
Pafos have won just one of their seven matches, but they still have a chance of qualifying for the play-offs.
Slavia Prague are three points and three places behind their hosts and are still looking for their first win in the competition this season.
Score Prediction: Pafos 2-1 Slavia Prague.