Yorkshire's director of cricket Martyn Moxon, first-team coach Andrew Gale and all members of the coaching staff have left the club following Azeem Rafiq's racism allegations.
A 100-page independent report in early November upheld that Rafiq had been victim of "racial harassment and bullying" during his time at Yorkshire.
Former chairman Roger Hutton resigned with immediate effect over Yorkshire's response to the investigation, with new chair Kamlesh Patel tasked with changing the culture at the club.
Chief executive Mark Arthur resigned from his position last month, before Gale was suspended pending investigation over a historical tweet, while Moxon took sick leave due to stress.
Yorkshire announced on Friday that Moxon and Gale have left the club, in addition to all members of the coaching staff and the backroom medical team.
A new director of cricket is the immediate priority, according to Patel, who is also recruiting an entire new coaching team for the upcoming season.
"Significant change is required at Yorkshire County Cricket Club and we are committed to taking whatever action is necessary to regain trust," Patel said in a statement on the county's official website.
"The decisions announced today were difficult to make but are in the best interests of the club. Without making important changes to how we are run, we cannot move on from the past to become a culture which is progressive and inclusive.
"We want to make Yorkshire County Cricket Club a place for everyone, from all backgrounds. To do this, we need to rebuild our culture and instil positive values in everyone associated with Yorkshire.
"We are determined to learn from the mistakes of the past to become a club which people can trust.
"We are hoping to announce a new director of cricket in the coming days. We have a huge rebuilding job to do but we are confident that this heralds a step forward towards a brighter future."