Eden Hazard and Sergio Ramos were named in the Real Madrid starting line-up to face Chelsea in the Champions League semi-final second leg.
Belgium star Hazard was only involved as a second-half substitute during the 1-1 draw with his former club in the first leg in Spain.
The 30-year-old has only started nine games in all competitions in a season impacted by a succession of injuries and a positive test for coronavirus.
Madrid captain Ramos, who has not played since sustaining a calf injury during the March international break, was chosen to partner Eder Militao at the heart of defence as the injured Raphael Varane missed out. Ferland Mendy returned at left-back, with Nacho Fernandez on the right of the defence.
Hazard was joined in attack by Karim Benzema, who scored Madrid's equaliser in the first leg, and Vinicius Junior in front of the traditional midfield trio of Luka Modric, Toni Kroos and Casemiro.
Chelsea chose Timo Werner and Kai Havertz in attack, supported by Mason Mount, as head coach Thomas Tuchel selected an apparent 3-4-3 system.
Christian Pulisic had to be content with a place on the bench despite opening the scoring in the tie.
Madrid have not beaten Chelsea in four previous European matches.