Cole Palmer faces a further six weeks out ahead of Chelsea's trip to Nottingham Forest
Manchester City will be without Rodri, while Jack Grealish sits out for Everton
Martin Odegaard misses Arsenal's game at Fulham with a knee injury
The Premier League returns for gameweek eight, which features seven matches on Saturday, two on Sunday and Monday's London derby between West Ham and Brentford.
Chelsea have received more bad news on Cole Palmer, who will miss out at Nottingham Forest, while Giorgi Mamardashvili is expected to be in between the sticks for Liverpool at home to Manchester United.
We have picked out some standout team news for the weekend's key fixtures.
Nottingham Forest vs Chelsea (Saturday, 12.30pm)
Enzo Maresca has revealed that Chelsea will be without Palmer for a further six weeks due to the groin injury he aggravated in September's defeat at Manchester United.
Palmer missed four matches before the international break and is now unlikely to feature until December.
However, Maresca says Tosin Adarabioyo, Wesley Fofana and Andrey Santos are available, as is club captain Reece James, who could make his 200th appearance for his boyhood club.
Forest boss Ange Postecoglou's pre-match press conference was dominated by chatter about whether he will still be in a job if his winless start at the City Ground is extended to eight games.
Former Chelsea youngster Ola Aina is sidelined for Forest with a hamstring injury, while Oleksandr Zinchenko (groin) and Douglas Luiz (hamstring) are doubts.
Manchester City vs Everton (Saturday, 3pm)
All eyes will be on in-form Erling Haaland, with the Norwegian having already netted 12 times for Manchester City this season and returning to club action after scoring a hat-trick in his country's 5-0 win over Israel.
However, Pep Guardiola is again without Haaland's most obvious rival for City's MVP award, Rodri, who came off with an injury in the 1-0 win at Brentford on October 5.
Nico Gonzalez could deputise in midfield but there is better news on Omar Marmoush and Rayan Ait-Nouri, who are set to be available for the first time since August.
Everton manager David Moyes may also need to be creative with his selection due to on-loan Jack Grealish being ineligible to face his parent club.
Kiernan Dewsbury-Hall returns from suspension, while Jarrad Branthwaite and Merlin Rohl are "back on the grass". However, Nathan Patterson is again out.
Fulham vs Arsenal (Saturday, 5.30pm)
Arsenal boss Mikel Arteta has confirmed that Martin Odegaard faces an unspecified spell on the sidelines with a knee injury.
Kai Havertz, Noni Madueke and Gabriel Jesus are all long-term absentees but there is some good news for the Gunners heading into Saturday's late game, with defender Piero Hincapie available following a groin issue.
Fulham will be without Sasa Lukic (unknown), Rodrigo Muniz (thigh) and Antonee Robinson (knee).
Samuel Chukwueze sustained a calf injury playing for Nigeria, while Raul Jimenez (hip) and Kenny Tete (knee) are also doubts.
Liverpool vs Manchester United (Sunday, 4.30pm)
Liverpool boss Arne Slot has confirmed goalkeeper Alisson Becker faces another fortnight out with the injury he sustained in the Champions League defeat at Galatasaray.
Giorgi Mamardashvili will continue to deputise in goal against Manchester United on Sunday. There is more positive news on Ryan Gravenberch, who Slot says is "completely fit" despite coming off at half-time in the Netherlands' 4-0 win over Finland last Sunday.
United defender Lisandro Martinez is close to returning from a knee injury, but this trip to Anfield comes too soon, while fellow former Ajax man Noussair Mazraoui is a doubt.
Senne Lammens impressed on his debut, a 2-0 win over Sunderland, and could again start for the Red Devils.
