West Ham's trip to Manchester United headlines tonight's slate of Carabao Cup third round fixtures.
And after QPR and Stoke pulled off upsets on Tuesday, the likes of Swansea, AFC Wimbledon and Millwall will be hoping for similar performances.
LiveScore take a look at all six of tonight's fixtures.
Brighton vs Swansea
Premier League surprise package Brighton host Swansea as they look to reach the EFL Cup fourth round for a second successive season.
The Seagulls have not achieved that feat since the 1978-79 and 1979-80 seasons under Alan Mullery but will be confident of doing so at the Amex.
They did the double over the Swans four seasons ago when they were both in the top flight, though the hosts did lose their only previous League Cup meeting 3-0 in 2008.
Russell Martin was appointed at Swansea on the eve of the season and has had a mixed start to life in South Wales.
But Saturday’s 3-3 draw at Luton will inject them with plenty of confidence after they found themselves 3-0 down at half-time.
Arsenal vs AFC Wimbledon
Arsenal and AFC Wimbledon meet for the first time in competitive football since the visitors were formed following Wimbledon FC’s move to Milton Keynes.
And the Gunners have won their past nine first meetings with English opponents, stretching back to 1987 when they beat Wimbledon 3-1.
Back-to-back Premier League victories over Norwich and Burnley have eased the pressure on Mikel Arteta, who knows he can still ill-afford a slip-up at the Emirates.
Changes are likely for the hosts with the lack of European football making this the perfect opportunity for fringe players to stake their claim.
Not that the Dons will be a pushover, with Mark Robinson’s outfit sitting seventh in League One despite defeat to Plymouth at the weekend.
Chelsea vs Aston Villa
Chelsea and Aston Villa lock horns for the second time this month as Dean Smith’s side look to exact revenge for the 3-0 Premier League defeat.
It is the first League Cup meeting between the duo since the 2006-07 campaign when the Blues progressed from the fourth-round tie.
And given the Stamford Bridge outfit have won all 10 of their previous third-round games stretching back to a 2010-11 defeat to Newcastle, the smart money is on the hosts.
But Thomas Tuchel will certainly view the competition as the least important of four as the Blues look to win the Premier League, retain the Champions League and right the wrongs of last season’s FA Cup final defeat to Leicester.
Smith, too, is likely to be keen to make changes and Cameron Archer, 19, may get the nod again after netting a hat-trick in the 6-0 rout of Barrow in the previous round.
Manchester United vs West Ham United (7.45pm, Sky Sports)
Just three days after Mark Noble’s dramatic penalty miss in the Premier League, Manchester United and West Ham do it all again at Old Trafford.
But with both teams playing in Europe and in the middle of a hectic September, there will be plenty of different faces on display tonight.
Jesse Lingard may play from the start after his late winner downed the Hammers in his first visit since his successful loan spell, while Noble may handed the chance to make amends for his stoppage-time miss.
If West Ham are to progress they need to end a 17-game winless run at the Red Devils, stretching all the way back to a Carlos Tevez-inspired victory that saw them avoid relegation in 2007.
David Moyes has won each of his last three third round ties — all of which have come at different clubs, including Manchester United in 2013.
Millwall vs Leicester
Millwall have the chance to the reach the fourth round for the first time in 16 years if they can upset Leicester at The Den.
The Lions will take heart from their 1-0 victory over the Foxes, who were Premier League champions at the time, in the FA Cup in 2016-17.
They have not hit top form in the league though, with three draws in a row and just one win in the Championship so far.
And Leicester’s record at opposition from lower leagues in this tournament is imperious, with 18 wins from their past 20 away ties.
Despite the two clubs meeting 43 times in their history, this is the first time they have clashed in the EFL Cup.
Wolves vs Tottenham
Nuno Espirito Santo heads back to former club Wolves for the second time in just two months as Tottenham boss.
The Portuguese enjoyed his first trip to Molineux as Spurs picked up a 1-0 win thanks to Dele Alli’s penalty.
And with Spurs winning on eight of their past 11 trips to the Black Country, losing only once, he will be confident of picking up a first win in four games in all competitions.
Wolves have often struggled against fellow top-flight opposition in the EFL Cup, losing their last seven such ties.
New boss Bruno Lage will be keen to pick up a morale-boosting victory though after suffering four defeats in five Premier League games.